“extension of Platelet Storage: Fact or Fantasy”
نویسنده
چکیده
منابع مشابه
تاثیر فیلتراسیون پیش از ذخیره کردن بر فعال شدن پلاکت‌ها در فراورده‌های پلاکتی
Preparation conditions and platelet storage for transfusion may cause platelet activation, which contributes to decreased ability of stored platelet to function and survive in vivo after transfusion compared with that seen with freshly prepared platelets. Using flowcytometry, we investigated platelet membrane expression of CD62P, CD63 in platelet stored for up to 3 days under standard blood ba...
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Background: The purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (PCs) on major platelet receptors CD42b and CD41/CD61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (PF3) assay. Materials and Methods: Six random units of conventional platelet conce...
متن کاملEvaluation of microRNAs; mir223, mir222 and mir92a levels in the Platelet-derived microparticles in the Platelet concentrates produced by Platelet Rich Plasma method during storage
Abstract Background and Objectives Platelets release microparticles containing cellular components, including microRNAs, during storage. Assessment of these microRNAs is one of the markers for evaluation of platelet storage lesions. The aim of the present study was to evaluate the level of changes in the expression of mir-223, mir-92a and mir-222 during storage in platelets prepared by platele...
متن کاملAn Overview on Platelet-derived Microparticles in Platelet Concentrates: blood collection, method preparation and storage
Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that may change platelet efficacy and safety issues. High shear stress could cause shedding of PMPs from the platelet plasma membrane, platelet aggregation, and activation of the co...
متن کاملPlatelet Factor 3 Based-clotting Time Assay as a Quality Marker for Long-term Storage of Platelet Concentrates
Background: Platelets rapidly lose their qualities usually after 5 day of storage. Different standard methods have been recommended to check the quality of platelets during storage which some of them show better correlation with other quality markers during storage. The purpose of this study was to demonstrate if platelet factor 3 (PF3) assay could be an indicator of storage lesion and provide ...
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تاریخ انتشار 2002